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1)  Age: Higher the age, less is the weight loss
2) Genetic and family factors: If any of your close relatives have lost weight well, so will you.
3) Diabetes: Reduces the chances of weight loss.
4) Depression and medications: Both reduce weight loss and encourage weight gain. it is better to consult a psychiatrist, choosing medicines that don’t promote weight gain.
5) Smoking: Actually helps weight loss, though it by itself is bad for your health.
6) Physical Activity: Regular exercises, especially weight training helps immensely in achieving weight loss.